Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ERN1 | O75460 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17748296 | 0.90 | LMNA (0.47) | LMNACXCR2BRD4L3MBTL1KMT2A | |
| SCHEMBL21780251 | 0.82 | BRD4 (0.47) | LMNACXCR2BRD4L3MBTL1KMT2A | |
| SCHEMBL6566957 | 0.81 | TSHR (0.55) | CXCR2BRD4L3MBTL1KMT2AKDM4E | |
| SCHEMBL26409544 | 0.81 | POLB (0.56) | LMNACXCR2L3MBTL1KMT2AALOX5 | |
| SCHEMBL21780290 | 0.79 | MAPK1 (0.51) | KMT2AALOX5CA1CA9HTT | |
| SCHEMBL11785384 | 0.79 | HTR2A (0.41) | LMNABRD4L3MBTL1KMT2AALOX5 | |
| SCHEMBL11785377 | 0.79 | HTR2A (0.41) | LMNABRD4L3MBTL1KMT2AALOX5 | |
| SCHEMBL30211643 | 0.78 | ERN1 (0.54) | CXCR2L3MBTL1KMT2AHDAC1ERN1 | |
| SCHEMBL3424158 | 0.78 | ERN1 (0.54) | CXCR2L3MBTL1KMT2AHDAC1ERN1 | |
| SCHEMBL27496683 | 0.78 | LMNA (0.61) | LMNAL3MBTL1KDM4EJAK2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5049280-A | 2,3-dihydroxyterephthalamides as highly effective metal ion sequestering compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1991-09-17 | — | — | US | disclosed |