Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 5/20 | 0.59 |
| ▸ | GLI1 | P08151 | 1/20 | 0.52 |
| ▸ | GLI2 | P10070 | 1/20 | 0.52 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.51 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.51 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.51 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2772929 | 0.84 | FDFT1 (0.66) | FDFT1GLI1GLI2PLAAT3PLAAT5 | |
| SCHEMBL10106169 | 0.82 | MTNR1A (0.68) | FDFT1AKR1C3 | |
| SCHEMBL17040294 | 0.81 | GLI1 (0.64) | FDFT1GLI1GLI2PLAAT3PLAAT5 | |
| SCHEMBL5354570 | 0.79 | FDFT1 (0.57) | FDFT1GLI1GLI2PLAAT3PLAAT5 | |
| SCHEMBL17037435 | 0.79 | GLI1 (0.61) | FDFT1GLI1GLI2PLAAT3PLAAT5 | |
| SCHEMBL9666803 | 0.79 | CES2 (0.53) | — | |
| SCHEMBL24708505 | 0.78 | SMN1; SMN2 (0.61) | FDFT1GLI1GLI2PLAAT3PLAAT5 | |
| SCHEMBL2774246 | 0.77 | FDFT1 (0.61) | FDFT1GLI1GLI2PLAAT3PLAAT5 | |
| SCHEMBL4527233 | 0.76 | FDFT1 (0.60) | FDFT1GLI1GLI2PLAAT3PLAAT5 | |
| SCHEMBL9782174 | 0.76 | CNR1 (0.52) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066658-A | Enzyme Inhibitors; Bronchodilators; Antiinflammatory Agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1991-11-19 | — | — | US | disclosed |