Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9781856 | 0.85 | RAB9A (0.47) | HPGDNPC1RAB9ADAOLMNA | |
| SCHEMBL1520458 | 0.79 | HPGD (0.69) | HPGDNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL1520453 | 0.79 | HPGD (0.69) | HPGDNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL1520457 | 0.79 | HPGD (0.69) | HPGDNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11227790 | 0.79 | RAB9A (0.52) | HPGDNPC1RAB9ADAOLMNA | |
| SCHEMBL11523638 | 0.74 | CES2 (0.52) | HPGDNPC1RAB9ADAOLMNA | |
| SCHEMBL11523637 | 0.74 | CES2 (0.52) | HPGDNPC1RAB9ADAOLMNA | |
| SCHEMBL11180687 | 0.71 | HPGD (0.53) | HPGDNPC1RAB9ALMNASMN1; SMN2 | |
| SCHEMBL11611090 | 0.71 | HPGD (0.44) | HPGDNPC1RAB9ADAOLMNA | |
| SCHEMBL11180686 | 0.71 | HPGD (0.53) | HPGDNPC1RAB9ALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4992544-A | Intermediates for b-lactam antibiotics and b-lactamase inhibitor | UNIVERSITY OF NOTRE DAME DU LAC (US) | 1991-02-12 | — | — | US | disclosed |