Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.30 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.30 |
| ▸ | ITGAL | P20701 | 1/20 | 0.30 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783686 | 0.93 | IDO1 (0.38) | IDO1CYP11B2PKMMEN1KMT2A | |
| SCHEMBL9783029 | 0.84 | IDO1 (0.32) | IDO1CYP11B2 | |
| SCHEMBL9783273 | 0.75 | CYP3A4 (0.36) | IDO1CYP17A1CYP3A4 | |
| SCHEMBL9783548 | 0.68 | CYP17A1 (0.33) | IDO1CYP11B2PKMCYP17A1CYP3A4 | |
| SCHEMBL9783417 | 0.67 | L3MBTL1 (0.32) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL9783367 | 0.59 | ALDH1A1 (0.46) | IDO1ADRA1DADRA1AADRA1BCYP3A4 | |
| SCHEMBL30514820 | 0.56 | CA1 (0.57) | MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL71009 | 0.56 | CA1 (0.57) | MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL9783836 | 0.55 | CYP3A4 (0.39) | IDO1CYP17A1CYP3A4 | |
| SCHEMBL9783013 | 0.54 | CYP17A1 (0.41) | IDO1CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |