Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | NMT1 | P30419 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL786747 | 0.86 | HDAC4 (0.52) | KDM4EHDAC4BRD4ESR1RIPK2 | |
| SCHEMBL5921550 | 0.84 | HDAC4 (0.51) | KDM4EHDAC4BRD4ESR1RIPK2 | |
| Hydrochloric Acid SCHEMBL28830016 | 0.84 | HDAC4 (0.51) | KDM4EHDAC4BRD4ESR1RIPK2 | |
| SCHEMBL9281044 | 0.83 | HDAC4 (0.54) | KDM4EHDAC4BRD4ESR1RIPK2 | |
| Phosphoric Acid SCHEMBL17964489 | 0.77 | HDAC4 (0.52) | KDM4EHDAC4BRD4ESR1RIPK2 | |
| Pentane SCHEMBL19922705 | 0.77 | TSHR (0.53) | KDM4EHDAC4BRD4ESR1RIPK2 | |
| SCHEMBL9783096 | 0.75 | HDAC4 (0.45) | KDM4EHDAC4BRD4ESR1RIPK2 | |
| SCHEMBL14002165 | 0.74 | NMT1 (0.43) | KDM4EHDAC4BRD4KDM5BRIPK2 | |
| SCHEMBL14412223 | 0.73 | NMT1 (0.52) | KDM4EHDAC4BRD4RIPK2NPC1 | |
| Quinoline SCHEMBL28194485 | 0.73 | ALDH1A1 (0.53) | KDM4EHDAC4BRD4ESR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |