Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.47 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5921550 | 0.98 | HDAC4 (0.51) | HDAC4BRD4ESR1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL28830016 | 0.98 | HDAC4 (0.51) | HDAC4BRD4ESR1NPC1RAB9A | |
| SCHEMBL9281044 | 0.96 | HDAC4 (0.54) | HDAC4BRD4ESR1NPC1RAB9A | |
| Pentane SCHEMBL19922705 | 0.89 | TSHR (0.53) | HDAC4BRD4ESR1NPC1RAB9A | |
| Phosphoric Acid SCHEMBL17964489 | 0.89 | HDAC4 (0.52) | HDAC4BRD4ESR1NPC1RAB9A | |
| SCHEMBL9783096 | 0.88 | HDAC4 (0.45) | HDAC4BRD4ESR1NPC1RAB9A | |
| SCHEMBL9783100 | 0.86 | KDM4E (0.47) | HDAC4BRD4ESR1NPC1RAB9A | |
| SCHEMBL14412223 | 0.85 | NMT1 (0.52) | HDAC4BRD4NPC1RAB9AKDM4E | |
| Quinoline SCHEMBL28194485 | 0.85 | ALDH1A1 (0.53) | HDAC4BRD4ESR1NPC1RAB9A | |
| SCHEMBL18937226 | 0.83 | ALDH1A1 (0.44) | HDAC4BRD4ESR1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 641 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111606855-B | N-heterocyclic carbene carboxylate bidentate ligand, bidentate ruthenium complex, preparation methods and application of N-heterocyclic carbene carboxylate bidentate ligand and bidentate ruthenium complex in catalysis of carboxylic acid-alkyne addition | 首都师范大学 | 2021-07-27 | — | — | CN | claimed |
| CN-111606855-A | N-heterocyclic carbene carboxylate bidentate ligand, bidentate ruthenium complex, preparation methods and application of N-heterocyclic carbene carboxylate bidentate ligand and bidentate ruthenium complex in catalysis of carboxylic acid-alkyne addition | 首都师范大学 | 2020-09-01 | — | — | CN | claimed |
| CN-106065161-B | A kind of composition epoxy resin of good insulating and application thereof | 江门市新会区新日旭电子材料有限公司 | 2018-07-31 | — | — | CN | claimed |
| CN-105164125-B | 2-phenyl or 2-heteroaryl imidazo [1,2-a ] pyridine derivatives | 豪夫迈·罗氏有限公司 | 2017-10-13 | — | — | CN | claimed |
| CN-105229009-B | 2-phenylimidazo [1,2-A ] pyrimidines as imaging agents | 豪夫迈·罗氏有限公司 | 2017-09-29 | — | — | CN | claimed |
| CN-105189494-B | Imidazo[4,5-c]pyridine and pyrrolo[2,3-c]pyridine derivatives as SSAO inhibitors | 普罗克西梅根有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-106183237-A | A kind of preparation method of environment friendly CCL | 刘世超 | 2016-12-07 | — | — | CN | claimed |
| CN-106065162-A | A kind of Halogen-free antibacterial composition epoxy resin and application thereof | 刘世超 | 2016-11-02 | — | — | CN | claimed |
| CN-106065161-A | A kind of composition epoxy resin of good insulating and application thereof | 刘世超 | 2016-11-02 | — | — | CN | claimed |
| CN-105229009-A | 2-phenylimidazo [1,2-A ] pyrimidines as imaging agents | HOFFMANN LA ROCHE | 2016-01-06 | — | — | CN | claimed |
| EP-1799677-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | Ranbaxy Laboratories Limited (IN) | 2007-06-27 | — | — | EP | claimed |
| WO-2007044447-A2 | COMPOSITION AND METHOD FOR SELECTIVELY ETCHING GATE SPACER OXIDE MATERIAL | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2007-04-19 | — | — | WO | claimed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | claimed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | claimed |
| WO-2006038100-A1 | OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS | RANBAXY LABORATORIES LIMITED (IN) | 2006-04-13 | — | — | WO | claimed |
| JP-2002535357-A | — | — | 2002-10-22 | — | — | JP | claimed |
| EP-1143943-A3 | P53 INHIBITORS AND THEIR USE FOR THE TREATMENT OF CANCER, HYPERTHERMIA, HYPOXIA, A BURN, TRAUMA TO THE CENTRAL NERVOUS SYSTEM, A SEIZURE, ACUTE INFLAMMATION, TISSUE AGEING, PRESERVATION OF ORGANS FOR TRANSPLANT AND PREPARATION OF A HOST FOR BONE MARROW TRANSPLANT | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2002-09-11 | — | — | EP | claimed |
| EP-1143943-A2 | P53 INHIBITORS AND THEIR USE FOR THE TREATMENT OF CANCER, HYPERTHERMIA, HYPOXIA, A BURN, TRAUMA TO THE CENTRAL NERVOUS SYSTEM, A SEIZURE, ACUTE INFLAMMATION, TISSUE AGEING, PRESERVATION OF ORGANS FOR TRANSPLANT AND PREPARATION OF A HOST FOR BONE MARROW TRANSPLANT | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2001-10-17 | — | — | EP | claimed |
| WO-2000044364-A2 | P53 INHIBITORS AND THEIR USE FOR THE TREATMENT OF CANCER, HYPERTHERMIA, HYPOXIA, A BURN, TRAUMA TO THE CENTRAL NERVOUS SYSTEM, A SEIZURE, ACUTE INFLAMMATION, TISSUE AGEING, PRESERVATION OF ORGANS FOR TRANSPLANT AND PREPARATION OF A HOST FOR BONE MARROW TRANSPLANT | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-08-03 | — | — | WO | claimed |
| US-5870275-A | CONTAINING A QUATERNARY AMIDINE GROUP | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1999-02-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | HDAC4 3363/4885BRD4 3294/4885ESR1 4728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.