Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 12/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783949 | 0.91 | TAAR1 (0.40) | CYP19A1TAAR1 | |
| SCHEMBL9783498 | 0.75 | CYP19A1 (0.39) | CYP19A1TAAR1 | |
| SCHEMBL9783336 | 0.74 | CYP19A1 (0.40) | CYP19A1TAAR1 | |
| SCHEMBL9783014 | 0.74 | CYP19A1 (0.43) | CYP19A1TAAR1 | |
| SCHEMBL6954666 | 0.70 | F2RL1 (0.43) | — | |
| SCHEMBL954931 | 0.70 | F2RL1 (0.46) | CYP19A1 | |
| SCHEMBL9783927 | 0.68 | MTOR (0.41) | TAAR1MEN1KMT2A | |
| SCHEMBL8653269 | 0.66 | CYP19A1 (0.42) | CYP19A1 | |
| SCHEMBL6934137 | 0.64 | TAAR1 (0.52) | TAAR1 | |
| SCHEMBL954734 | 0.64 | CHRM2 (0.45) | TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |