Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.40 |
| ▸ | HRH1 | P35367 | 5/20 | 0.40 |
| ▸ | HTR2A | P28223 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SCN1A | P35498 | 1/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783659 | 0.85 | CYP19A1 (0.40) | CYP19A1HRH1HTR2ATAAR1LMNA | |
| SCHEMBL9783949 | 0.81 | TAAR1 (0.40) | CYP19A1HTR2ACHRM2SLC6A2SLC6A4 | |
| SCHEMBL9783173 | 0.74 | CYP19A1 (0.44) | CYP19A1TAAR1 | |
| SCHEMBL9783731 | 0.71 | CYP19A1 (0.50) | CYP19A1HRH1HTR2ASIGMAR1MTOR | |
| SCHEMBL9783774 | 0.71 | HRH1 (0.38) | CYP19A1HRH1HTR2ASIGMAR1TBXAS1 | |
| SCHEMBL9783927 | 0.70 | MTOR (0.41) | CHRM2SLC6A2SLC6A4SCN1ASCN2A | |
| SCHEMBL953334 | 0.67 | CHRM2 (0.43) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| SCHEMBL9659736 | 0.67 | HRH1 (0.55) | HRH1HTR2ACHRM2SLC6A2SLC6A4 | |
| SCHEMBL9783014 | 0.67 | CYP19A1 (0.43) | CYP19A1TAAR1MTORADKNISCH | |
| SCHEMBL9783498 | 0.66 | CYP19A1 (0.39) | CYP19A1TAAR1NISCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |