Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.71 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.71 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783186 | 0.90 | HRH3 (0.57) | HRH3TAAR1HRH4CYP3A4MAPT | |
| SCHEMBL1034848 | 0.84 | HRH3 (1.00) | HRH3TAAR1HRH4CYP3A4MAPT | |
| SCHEMBL9783345 | 0.79 | HRH3 (0.58) | HRH3HRH4 | |
| SCHEMBL9783386 | 0.75 | ADRA2A (0.43) | HRH3TAAR1HRH4CYP3A4CYP2D6 | |
| SCHEMBL9783723 | 0.72 | HRH3 (0.49) | HRH3TAAR1HRH4 | |
| SCHEMBL9783259 | 0.72 | HRH3 (0.73) | HRH3TAAR1HRH4CYP3A4MAPT | |
| SCHEMBL9783641 | 0.71 | TAAR1 (0.46) | HRH3TAAR1HRH4ADRA1A | |
| SCHEMBL2626857 | 0.71 | HRH3 (1.00) | HRH3TAAR1HRH4CYP2D6 | |
| SCHEMBL1266034 | 0.71 | PCSK9 (0.43) | CYP3A4 | |
| SCHEMBL9783606 | 0.71 | TAAR1 (0.71) | TAAR1MAPTSMN1; SMN2CYP2D6ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |