Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 1.00 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 1.00 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.69 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783259 | 0.85 | HRH3 (0.73) | HRH3TAAR1HRH4CYP3A4MAPT | |
| SCHEMBL2626857 | 0.84 | HRH3 (1.00) | HRH3TAAR1HRH4CYP2D6 | |
| SCHEMBL9783245 | 0.84 | HRH3 (0.71) | HRH3TAAR1HRH4CYP3A4MAPT | |
| Immethridine SCHEMBL29462340 | 0.83 | HRH3 (1.00) | HRH3TAAR1HRH4CYP3A4MAPT | |
| SCHEMBL10217408 | 0.82 | HRH3 (0.69) | HRH3TAAR1HRH4CYP3A4MAPT | |
| Immethridine SCHEMBL30053193 | 0.82 | CYP3A4 (1.00) | HRH3TAAR1HRH4CYP3A4MAPT | |
| SCHEMBL224745 | 0.82 | TAAR1 (1.00) | HRH3TAAR1HRH4 | |
| SCHEMBL8009818 | 0.80 | HRH3 (0.67) | HRH3TAAR1HRH4CYP3A4MAPT | |
| SCHEMBL28759658 | 0.80 | HRH3 (1.00) | HRH3TAAR1HRH4CYP3A4MAPT | |
| SCHEMBL2536900 | 0.79 | HRH3 (0.93) | HRH3TAAR1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368494-A | Methods, compositions and uses of novel FYN kinase inhibitors | 沃伦·C·刘 | 2018-08-03 | — | — | CN | claimed |
| US-20260103459-A1 | SUBSTITUTED AZACYLES AS TRPM8 MODULATORS | GIVAUDAN SA (CH) | 2026-04-16 | — | — | US | disclosed |
| EP-4317135-A4 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | WEST CHINA HOSPITAL SICHUAN UNIV (CN) | 2025-07-30 | — | — | EP | disclosed |
| US-20240217936-A1 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2024-07-04 | — | — | US | disclosed |
| US-20240217936-A1 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2024-07-04 | — | — | US | disclosed |
| US-20240217936-A1 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | WEST CHINA HOSPITAL, SICHUAN UNIVERSITY (CN) | 2024-07-04 | — | — | US | disclosed |
| EP-4317135-A1 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | West China Hospital, Sichuan University (CN) | 2024-02-07 | — | — | EP | disclosed |
| EP-4317135-A1 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | West China Hospital, Sichuan University (CN) | 2024-02-07 | — | — | EP | disclosed |
| EP-4317135-A1 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | West China Hospital, Sichuan University (CN) | 2024-02-07 | — | — | EP | disclosed |
| CN-115197148-B | 5-benzyl imidazole compound and preparation method and application thereof | 四川大学华西医院 | 2023-12-12 | — | — | CN | disclosed |
| EP-1981880-B1 | USE OF 4-IMIDAZOLE DERIVATIVES FOR CNS DISORDERS | HOFFMANN LA ROCHE (CH) | 2010-02-24 | — | — | EP | disclosed |
| WO-2009129094-A2 | COMPOSITIONS CONTAINING ANTIVIRAL COMPOUNDS AND METHODS OF USING THE SAME | MALLINCKRODT INC. (US) | 2009-10-22 | — | — | WO | disclosed |
| US-20090258843-A1 | Compositions Containing Antiviral Compounds and Methods of Using the Same | MALLINCKRODT INC. (US) | 2009-10-15 | — | — | US | disclosed |
| US-20070197622-A1 | Methods for treating CNS disorders with 4-imidazole derivatives | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2007-08-23 | — | — | US | disclosed |
| US-20070197622-A1 | Methods for treating CNS disorders with 4-imidazole derivatives | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2007-08-23 | — | — | US | disclosed |
| WO-2007085556-A2 | USE OF 4-IMIDAZOLE DERIVATIVES FOR CNS DISORDERS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-08-02 | — | — | WO | disclosed |
| CN-1181069-C | Novel inhibitors of farnesyl-protein transferase | ���鹫˾ | 2004-12-22 | — | — | CN | disclosed |
| CN-1346355-A | Novel inhibitors of farnesyl-protein transferase | SCHERING CORP (US) | 2002-04-24 | — | — | CN | disclosed |
| CN-1284066-A | Substituted imidazole derivatives having agonist-like activity at alpha 2B or 2B/2C adrenergic receptors | ALLERGEN SALES INC (US) | 2001-02-14 | — | — | CN | disclosed |
| CN-1035113-A | The heterogeneous ring compound that is used for the treatment of | WELLCOME FOUND (GB) | 1989-08-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260103459-A1 | SUBSTITUTED AZACYLES AS TRPM8 MODULATORS | TRPM8, TRPM7, TRPM5 | HRH3 602/4885TAAR1 236/4885HRH4 403/4885 |
| US-20090258843-A1 | Compositions Containing Antiviral Compounds and Methods of Using the Same | EIF2AK2, MAVS, IRF3 | HRH3 2765/4885TAAR1 4398/4885HRH4 2846/4885 |
| US-20070197622-A1 | Methods for treating CNS disorders with 4-imidazole derivatives | CRY1, GPR119, MTNR1A | HRH3 213/4885TAAR1 79/4885HRH4 109/4885 |
| US-20240217936-A1 | 5-BENZYLIMIDAZOLE COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF | CYP4F11, WASF2, CYP3A5 | HRH3 2479/4885TAAR1 4258/4885HRH4 1129/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.