Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.36 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783313 | 0.85 | MEN1 (0.33) | CYP19A1 | |
| SCHEMBL9783571 | 0.80 | CYP19A1 (0.40) | CYP19A1 | |
| SCHEMBL9783731 | 0.80 | CYP19A1 (0.50) | HRH1HTR2AHTR1BMTORCYP19A1 | |
| SCHEMBL9783336 | 0.71 | CYP19A1 (0.40) | HRH1HTR2AMTORCYP19A1SIGMAR1 | |
| SCHEMBL9783783 | 0.68 | CYP19A1 (0.48) | HRH1HTR2ACYP19A1 | |
| SCHEMBL9783659 | 0.62 | CYP19A1 (0.40) | HRH1HTR2ACYP19A1 | |
| SCHEMBL9073997 | 0.61 | HRH1 (0.71) | HRH1HTR2ACYP19A1SIGMAR1 | |
| SCHEMBL9783253 | 0.58 | AOC3 (0.50) | HRH1HTR1BMTORBRS3 | |
| SCHEMBL157808 | 0.58 | HRH1 (1.00) | HRH1HTR2AHTR1BSIGMAR1 | |
| SCHEMBL1293020 | 0.58 | SIGMAR1 (0.61) | HRH1HTR2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |