Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9783454 | 0.90 | ALOX15B (0.36) | CYP19A1SLC6A3OPRK1CYP3A4CACNA1C | |
| SCHEMBL9783939 | 0.79 | KDM4E (0.36) | CYP19A1KDM4ECYP17A1KMT2A | |
| SCHEMBL9783614 | 0.75 | CYP19A1 (0.36) | CYP19A1TSHRKDM4ESLC6A3SLC6A2 | |
| SCHEMBL9783721 | 0.71 | TLR8 (0.44) | CYP19A1CYP17A1MEN1ALDH1A1MAPT | |
| SCHEMBL9783925 | 0.71 | KDM4E (0.34) | KDM4ECYP17A1MEN1MAPTMAPK1 | |
| SCHEMBL9783376 | 0.70 | CYP2D6 (0.44) | CYP19A1KDM4ESLC6A3SLC6A2SLC6A4 | |
| SCHEMBL9784041 | 0.69 | MEN1 (0.34) | CYP19A1TSHRKDM4EMEN1CYP3A4 | |
| SCHEMBL9784157 | 0.66 | P2RX7 (0.32) | — | |
| SCHEMBL12562408 | 0.65 | MEN1 (0.41) | TSHRMEN1TP53HSP90AA1HPGD | |
| SCHEMBL9783705 | 0.64 | CYP19A1 (0.34) | CYP19A1MEN1MAPTHPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5051514-A | Complexing boranes and imidazoles | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-09-24 | — | — | US | disclosed |
| EP-0432987-A2 | Fungicidal organoborane imidazole compounds and intermediates therefor | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-06-19 | — | — | EP | disclosed |
| US-4983589-A | Fungicidal imidazole diphenylaliphaticboranes and derivatives thereof | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1991-01-08 | — | — | US | disclosed |