Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3141601 | 0.83 | DGAT1 (0.79) | DGAT1 | |
| SCHEMBL186201 | 0.79 | DGAT1 (0.46) | DGAT1MAOAMAOB | |
| SCHEMBL28714854 | 0.77 | DGAT1 (0.44) | DGAT1MAOAMAOB | |
| SCHEMBL29908023 | 0.77 | DGAT1 (0.44) | DGAT1MAOAMAOB | |
| SCHEMBL8678863 | 0.77 | DGAT1 (0.62) | DGAT1 | |
| SCHEMBL30496820 | 0.77 | DGAT1 (0.50) | DGAT1 | |
| SCHEMBL410733 | 0.76 | — | — | |
| SCHEMBL4356324 | 0.76 | DGAT1 (0.54) | DGAT1 | |
| SCHEMBL998622 | 0.76 | DGAT1 (0.61) | DGAT1 | |
| SCHEMBL16787839 | 0.76 | DGAT1 (0.61) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE33778-E | 1,3-dithietane-2-carboxylic acid penicillin and cephalosporin derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-12-24 | — | — | US | disclosed |
| US-RE32491-E | BACTERICIDES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1987-09-01 | — | — | US | disclosed |
| US-4414153-A | 1,3-Dithietane-2-carboxylic acid penicillin and cephalosporin derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1983-11-08 | — | — | US | disclosed |
| US-4404373-A | Process for the preparation of 7α-methoxy-7β-(1,3-diethietane-2-carboxamido)cephalosporanic acid derivatives | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1983-09-13 | — | — | US | disclosed |
| US-4263432-A | ANTIBIOTICS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-04-21 | — | — | US | disclosed |
| US-4198339-A | INTERMEDIATES FOR PENICILLINS AND CEPHALOSPORINS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1980-04-15 | — | — | US | disclosed |