Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | PLK1 | P53350 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | NAAA | Q02083 | 2/20 | 0.59 |
| ▸ | MLYCD | O95822 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | ESRRG | P62508 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.51 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5255837 | 0.96 | L3MBTL1 (0.64) | TMEM97SIGMAR1L3MBTL1PLK1POLB | |
| SCHEMBL27325924 | 0.96 | L3MBTL1 (0.64) | TMEM97SIGMAR1L3MBTL1PLK1POLB | |
| SCHEMBL16209245 | 0.96 | L3MBTL1 (0.64) | TMEM97SIGMAR1L3MBTL1PLK1POLB | |
| SCHEMBL9784422 | 0.92 | L3MBTL1 (0.71) | TMEM97SIGMAR1L3MBTL1PLK1NAAA | |
| SCHEMBL27284919 | 0.91 | L3MBTL1 (0.61) | TMEM97SIGMAR1L3MBTL1PLK1NAAA | |
| SCHEMBL9491031 | 0.89 | L3MBTL1 (0.71) | TMEM97SIGMAR1L3MBTL1PLK1NAAA | |
| SCHEMBL10949132 | 0.89 | PLK1 (0.70) | TMEM97SIGMAR1L3MBTL1PLK1NAAA | |
| SCHEMBL15174013 | 0.87 | THRA (0.59) | TMEM97SIGMAR1L3MBTL1PLK1NAAA | |
| SCHEMBL13375750 | 0.86 | L3MBTL1 (0.71) | TMEM97SIGMAR1L3MBTL1PLK1NAAA | |
| SCHEMBL10948379 | 0.86 | PLK1 (0.70) | TMEM97SIGMAR1L3MBTL1PLK1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5003106-A | Antiatherosclerotic ureas and thioureas | AMERICAN CYANAMID COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4623662-A | ANTICHOLESTEROL, ANTILIPEMIC | AMERICAN CYANAMID COMPANY (US) | 1986-11-18 | — | — | US | disclosed |