Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.48 |
| ▸ | BCHE | P06276 | 4/20 | 0.47 |
| ▸ | GUSB | P08236 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FPR3 | P25089 | 1/20 | 0.45 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sulfuric Acid SCHEMBL10335567 | 1.00 | HRH3 (0.58) | HRH3KDM4EGNAI3GNAO1GNAI1 | |
| Sulfuric Acid SCHEMBL28074244 | 0.98 | HRH3 (0.54) | HRH3KDM4EGNAI3GNAO1GNAI1 | |
| SCHEMBL29252320 | 0.94 | HRH3 (0.56) | HRH3KDM4EGNAI3GNAO1GNAI1 | |
| SCHEMBL30331433 | 0.94 | HRH3 (0.56) | HRH3KDM4EGNAI3GNAO1GNAI1 | |
| SCHEMBL29252145 | 0.94 | HRH3 (0.56) | HRH3KDM4EGNAI3GNAO1GNAI1 | |
| SCHEMBL29251816 | 0.94 | HRH3 (0.56) | HRH3KDM4EGNAI3GNAO1GNAI1 | |
| SCHEMBL30330091 | 0.94 | HRH3 (0.56) | HRH3KDM4EGNAI3GNAO1GNAI1 | |
| SCHEMBL29252756 | 0.94 | HRH3 (0.56) | HRH3KDM4EGNAI3GNAO1GNAI1 | |
| SCHEMBL21829189 | 0.92 | HRH3 (0.52) | HRH3KDM4EGNAI3GNAO1GNAI1 | |
| SCHEMBL16700927 | 0.92 | HRH3 (0.52) | HRH3KDM4EGNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997672-A | Cetylpyridinium chloride | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 1991-03-05 | — | — | US | disclosed |
| EP-0305469-A4 | SALT TASTE ENHANCER | — | 1990-12-27 | — | — | EP | disclosed |
| EP-0305469-A1 | SALT TASTE ENHANCER | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1989-03-08 | — | — | EP | disclosed |
| WO-1988006850-A1 | SALT TASTE ENHANCER | CENTER FOR INNOVATIVE TECHNOLOGY (US) | 1988-09-22 | — | — | WO | disclosed |