Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | FPR3 | P25089 | 2/20 | 0.48 |
| ▸ | FPR2 | P25090 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29252756 | 0.98 | HRH3 (0.56) | HRH3KDM4EFPR3FPR2ALDH1A1 | |
| SCHEMBL29251816 | 0.98 | HRH3 (0.56) | HRH3KDM4EFPR3FPR2ALDH1A1 | |
| SCHEMBL29252145 | 0.98 | HRH3 (0.56) | HRH3KDM4EFPR3FPR2ALDH1A1 | |
| SCHEMBL29252320 | 0.98 | HRH3 (0.56) | HRH3KDM4EFPR3FPR2ALDH1A1 | |
| SCHEMBL30330091 | 0.98 | HRH3 (0.56) | HRH3KDM4EFPR3FPR2ALDH1A1 | |
| SCHEMBL30331433 | 0.98 | HRH3 (0.56) | HRH3KDM4EFPR3FPR2ALDH1A1 | |
| SCHEMBL30331344 | 0.98 | FPR3 (0.49) | HRH3KDM4EFPR3FPR2ALDH1A1 | |
| SCHEMBL16700927 | 0.96 | HRH3 (0.52) | HRH3KDM4EFPR3FPR2BCHE | |
| SCHEMBL29251654 | 0.96 | HRH3 (0.52) | HRH3KDM4EFPR3FPR2BCHE | |
| SCHEMBL29251626 | 0.96 | HRH3 (0.52) | HRH3KDM4EFPR3FPR2BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117999475-A | Electrochemical gas sensor and electrolyte for electrochemical gas sensor | 德尔格安全股份两合公司 | 2024-05-07 | — | — | CN | disclosed |
| WO-2023046704-A1 | ELECTROCHEMICAL GAS SENSOR AND ELECTROLYTE FOR AN ELECTROCHEMICAL GAS SENSOR | Dräger Safety AG & Co. KGaA (DE) | 2023-03-30 | — | — | WO | disclosed |
| WO-2020071553-A1 | ADHESIVE COMPOSITION FOR ASSEMBLING SPEAKER, METHOD FOR ASSEMBLING SPEAKER, AND SPEAKER | 東亞合成株式会社 | 2020-04-09 | — | — | WO | disclosed |
| CN-107108771-B | Two-liquid type solidification compound | 东亚合成株式会社 | 2019-08-16 | — | — | CN | disclosed |
| CN-109415602-A | 2- cyanoacrylate system adhesive composite | 东亚合成株式会社 | 2019-03-01 | — | — | CN | disclosed |
| CN-105579537-B | Adhesive composite | 东亚合成株式会社 | 2018-11-27 | — | — | CN | disclosed |
| CN-105593307-B | Hardening resin composition | 东亚合成株式会社 | 2018-07-27 | — | — | CN | disclosed |
| CN-107108771-A | Two-liquid type solidification compound | 东亚合成株式会社 | 2017-08-29 | — | — | CN | disclosed |
| CN-105579537-A | Adhesive composition | TOAGOSEI CO LTD | 2016-05-11 | — | — | CN | disclosed |