SCHEMBL978487

SCHEMBL978487

O=C1N[C@H]2[C@H](CS[C@H]2CCCCC(=O)OC(=O)O)N1

nearest known ligand 0.75

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 6/20 0.75
MEN1 O00255 1/20 0.74
ABL1 P00519 1/20 0.74
LMNA P02545 1/20 0.74
PKM P14618 1/20 0.74
IDE P14735 1/20 0.74
MAPK1 P28482 1/20 0.74
KMT2A Q03164 1/20 0.74
RIN1 Q13671 1/20 0.74
L3MBTL1 Q9Y468 1/20 0.74
HLCS P50747 6/20 0.61
CA12 O43570 5/20 0.51
CA1 P00915 5/20 0.51
CA2 P00918 5/20 0.51
CA9 Q16790 5/20 0.51
HPSE Q9Y251 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28119479 0.93 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
SCHEMBL21114407 0.93 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
SCHEMBL28283183 0.93 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
SCHEMBL21176811 0.93 TDP1 (0.81) TDP1MEN1ABL1LMNAPKM
SCHEMBL22265330 0.92 TDP1 (0.79) TDP1MEN1ABL1LMNAPKM
SCHEMBL28516361 0.91 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL4407437 0.90 TDP1 (0.87) TDP1MEN1ABL1LMNAPKM
SCHEMBL22290232 0.89 TDP1 (0.82) TDP1MEN1ABL1LMNAPKM
SCHEMBL28516340 0.89 TDP1 (0.73) TDP1MEN1ABL1LMNAPKM
SCHEMBL20473406 0.88 TDP1 (0.72) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US claimed
US-20250075170-A1 TARGETED MUTAGENESIS IN SPIRULINA Lumen Bioscience, Inc. 2025-03-06 US disclosed
US-12065638-B2 Targeted mutagenesis in spirulina Lumen Bioscience, Inc. (US) 2024-08-20 US disclosed
EP-3191581-B9 TARGETED MUTAGENESIS IN SPIRULINA LUMEN BIOSCIENCE INC (US) 2023-10-11 EP disclosed
EP-3191581-B1 TARGETED MUTAGENESIS IN SPIRULINA LUMEN BIOSCIENCE INC (US) 2023-06-07 EP disclosed
EP-3940057-A1 TARGETED MUTAGENESIS IN SPIRULINA Lumen Bioscience, Inc. (US) 2022-01-19 EP disclosed
CN-113717913-A Targeted mutagenesis in spirulina 流明生物科学公司 2021-11-30 CN disclosed
CN-106687578-B Targeted mutagenesis in spirulina 流明生物科学公司 2021-09-24 CN disclosed
US-20210047610-A1 CYANOBACTERIA HAVING IMPROVED PHOTOSYNTHETIC ACTIVITY Lumen Bioscience, Inc. 2021-02-18 US disclosed
US-10760045-B2 Cyanobacteria having improved photosynthetic activity Lumen Bioscience, Inc. (US) 2020-09-01 US disclosed
US-20100184169-A1 Modified Photosynthetic Microorganisms With Reduced Glycogen and Their Use in Producing Carbon-Based Products TARGETED GROWTH, INC. (US) 2010-07-22 US disclosed
WO-2010075440-A1 MODIFIED PHOTOSYNTHETIC MICROORGANISMS WITH REDUCED GLYCOGEN AND THEIR USE IN PRODUCING CARBON-BASED PRODUCTS TARGETED GROWTH, INC. (US) 2010-07-01 WO disclosed
WO-2010048568-A1 MODIFIED PHOTOSYNTHETIC MICROORGANISMS FOR PRODUCING TRIGLYCERIDES TARGETED GROWTH, INC. (US) 2010-04-29 WO disclosed
US-20100081178-A1 MODIFIED PHOTOSYNTHETIC MICROORGANISMS FOR PRODUCING TRIGLYCERIDES TARGETED GROWTH, INC. (US) 2010-04-01 US disclosed
EP-2150265-A1 INHIBITORS OF ACETYL-COA CARBOXYLASE FOR TREATMENT OF NEURONAL HYPOMETABOLISM Neuera Pharmaceuticals, Inc. (US) 2010-02-10 EP disclosed
WO-2008140828-A1 INHIBITORS OF ACETYL-COA CARBOXYLASE FOR TREATMENT OF NEURONAL HYPOMETABOLISM ACCERA, INC. (US) 2008-11-20 WO disclosed
EP-1960003-A2 TARGETED NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING General Electric Company (US) 2008-08-27 EP disclosed
US-20070140974-A1 Targeted nanoparticles for magnetic resonance imaging GENERAL ELECTRIC COMPANY (US) 2007-06-21 US disclosed
WO-2007069040-A2 TARGETED NANOPARTICLES FOR MAGNETIC RESONANCE IMAGING GENERAL ELECTRIC COMPANY (US) 2007-06-21 WO disclosed
US-20030007961-A1 Orthomolecular vitamin E derivatives WILBURN MICHAEL D (US) 2003-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030007961-A1 Orthomolecular vitamin E derivatives RBP4, RBP1, VDR TDP1 4155/4885MEN1 3493/4885ABL1 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.