Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423387 | 0.93 | MAPT (0.47) | MAPTRAB9ANPSR1TDP1KDM4E | |
| SCHEMBL28972068 | 0.89 | MAPT (0.57) | MAPTRAB9ANPSR1TDP1KDM4E | |
| SCHEMBL6125235 | 0.86 | MAPT (0.50) | MAPTRAB9ANPSR1TDP1KDM4E | |
| SCHEMBL9282972 | 0.85 | MAPT (0.49) | MAPTRAB9ANPSR1TDP1KDM4E | |
| SCHEMBL6125231 | 0.83 | MAPT (0.51) | MAPTRAB9ANPSR1TDP1KDM4E | |
| Phosphine SCHEMBL28088577 | 0.83 | MAPT (0.48) | MAPTRAB9ANPSR1TDP1KDM4E | |
| SCHEMBL15521372 | 0.82 | MAPT (0.47) | MAPTRAB9ANPSR1TDP1KDM4E | |
| SCHEMBL11483411 | 0.81 | KMT2A (0.46) | MAPTNPSR1HPGDALOX15HSD17B10 | |
| SCHEMBL1254116 | 0.80 | KMT2A (0.64) | MAPTRAB9ATDP1KDM4EPTK2B | |
| SCHEMBL30631651 | 0.79 | MAPT (0.59) | MAPTTDP1KDM4EPTK2BHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1094028-A | Selective PDE enzyme (IV) inhibitor catechol diether class | PFIZER (US) | 1994-10-26 | — | — | CN | disclosed |
| US-5041169-A | Comprising phenyl benzoate, solvent and activating agent, soldering printed circuit boards | COOKSON GROUP PLC (GB) | 1991-08-20 | — | — | US | disclosed |
| EP-0379290-A1 | Flux composition | COOKSON GROUP plc (GB) | 1990-07-25 | — | — | EP | disclosed |