Phosphine

Phosphine

SCHEMBL28088577

Cc1cc(C)c(C(=O)Oc2ccccc2)c(C)c1.P

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.48
RAB9A P51151 2/20 0.48
NPSR1 Q6W5P4 1/20 0.48
NSD2 O96028 1/20 0.46
HPGD P15428 2/20 0.44
ALOX15 P16050 2/20 0.44
HSD17B10 Q99714 2/20 0.44
NPC1 O15118 1/20 0.44
KMT2A Q03164 2/20 0.44
CYP3A4 P08684 2/20 0.44
MEN1 O00255 1/20 0.44
ALDH1A1 P00352 1/20 0.44
MAPK1 P28482 1/20 0.44
POLB P06746 2/20 0.43
PTK2B Q14289 2/20 0.43
RXFP1 Q9HBX9 1/20 0.43
KDM4E B2RXH2 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9282972 0.98 MAPT (0.49) MAPTRAB9ANPSR1NSD2HPGD
SCHEMBL9286049 0.88 CYP3A4 (0.55) MAPTRAB9ANPSR1NSD2HPGD
SCHEMBL15521372 0.84 MAPT (0.47) MAPTRAB9ANPSR1NSD2HPGD
SCHEMBL9785643 0.83 MAPT (0.51) MAPTRAB9ANPSR1NSD2HPGD
SCHEMBL2882316 0.81 SERPINE1 (0.46) MAPTHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL9426410 0.80 MAPT (0.44) MAPTRAB9ANPSR1NSD2NPC1
SCHEMBL28465210 0.80 NR3C1 (0.42) MAPTRAB9ANPSR1NPC1KMT2A
SCHEMBL28471130 0.80 POLB (0.54) MAPTNPSR1HPGDKMT2ACYP3A4
SCHEMBL10903986 0.79 NSD2 (0.51) MAPTRAB9ANPSR1NSD2HPGD
SCHEMBL28007881 0.79 HPGD (0.50) MAPTRAB9ANPSR1NSD2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108239296-A Hydrophobic rain-proof film of vehicle rearview mirror and preparation method thereof 武汉保丽量彩科技有限公司 2018-07-03 CN claimed
CN-105745236-A Adhesive, adhesive-backed member, and method for joining between members 3M创新有限公司 2016-07-06 CN disclosed