SCHEMBL9282972

SCHEMBL9282972

Cc1cc(C)c(C(=O)Oc2ccccc2)c(C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.49
RAB9A P51151 2/20 0.49
NPSR1 Q6W5P4 1/20 0.49
NSD2 O96028 1/20 0.47
HPGD P15428 2/20 0.46
ALOX15 P16050 2/20 0.46
HSD17B10 Q99714 2/20 0.46
NPC1 O15118 1/20 0.46
KMT2A Q03164 2/20 0.45
CYP3A4 P08684 2/20 0.45
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
MAPK1 P28482 1/20 0.45
PTK2B Q14289 2/20 0.44
POLB P06746 2/20 0.44
RXFP1 Q9HBX9 1/20 0.44
KDM4E B2RXH2 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphine SCHEMBL28088577 0.98 MAPT (0.48) MAPTRAB9ANPSR1NSD2HPGD
SCHEMBL9286049 0.90 CYP3A4 (0.55) MAPTRAB9ANPSR1NSD2HPGD
SCHEMBL15521372 0.86 MAPT (0.47) MAPTRAB9ANPSR1NSD2HPGD
SCHEMBL9785643 0.85 MAPT (0.51) MAPTRAB9ANPSR1NSD2HPGD
SCHEMBL2882316 0.83 SERPINE1 (0.46) MAPTHSD17B10KMT2AMEN1ALDH1A1
SCHEMBL9426410 0.81 MAPT (0.44) MAPTRAB9ANPSR1NSD2NPC1
SCHEMBL28465210 0.81 NR3C1 (0.42) MAPTRAB9ANPSR1NPC1KMT2A
SCHEMBL28471130 0.81 POLB (0.54) MAPTNPSR1HPGDKMT2ACYP3A4
SCHEMBL10903986 0.81 NSD2 (0.51) MAPTRAB9ANPSR1NSD2HPGD
SCHEMBL28007881 0.81 HPGD (0.50) MAPTRAB9ANPSR1NSD2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105399935-B Degradable light-cured resin performed polymer and preparation method, light-cured resin and preparation method 孝感市易生新材料有限公司 2017-07-11 CN claimed
CN-114940771-A Shell assembly, preparation method thereof and electronic equipment OPPO广东移动通信有限公司 2022-08-26 CN disclosed
CN-113950213-A Shell, preparation method thereof and electronic equipment OPPO广东移动通信有限公司 2022-01-18 CN disclosed
CN-113423213-A Shell assembly, preparation method thereof and electronic equipment OPPO广东移动通信有限公司 2021-09-21 CN disclosed
WO-2020118922-A1 METHOD FOR PREPARING BORIC ACID ESTER BASED ON LITHIUM COMPOUND 苏州大学 2020-06-18 WO disclosed
WO-2020113835-A1 METHOD FOR PREPARING BORIC ACID ESTER USING UNCATALYZED HYDROBORATION OF CARBOXYLIC ACID 苏州大学 2020-06-11 WO disclosed
CN-106715598-B Alkali-soluble resin, photosensitive resin composition and use thereof 耐涂可株式会社 2019-07-19 CN disclosed
CN-109065599-A A kind of display panel and preparation method thereof and display device 京东方科技集团股份有限公司 2018-12-21 CN disclosed
CN-104870569-B Pressure sensitive adhesive composition LG化学株式会社 2018-06-29 CN disclosed
CN-108102442-A One kind one applies cured imitative electroplating effect coating of UV and preparation method thereof 深圳市永盛辉实业有限公司 2018-06-01 CN disclosed
US-20170044160-A1 TETRACYCLINE COMPOUNDS TETRAPHASE PHARMACEUTICALS, INC. 2017-02-16 US disclosed
CN-104520378-B Radiation-curable formulations with high adhesion BASF SE (DE) 2016-11-30 CN disclosed
CN-106170279-A Photo-hardening artificial nail composition 株式会社樱花彩色笔 2016-11-30 CN disclosed
CN-104583815-B Carry lensed substrate and manufacture method thereof, and carry lensed fiber waveguide 日立化成株式会社 2016-10-26 CN disclosed
CN-104334344-B Optical component and for manufacturing the ultraviolet hardening adhesive of this optical component 日本化药株式会社 2016-10-19 CN disclosed
CN-105980490-A Radiation-curable inkjet ink set and inkjet recording method 富士胶片株式会社 2016-09-28 CN disclosed
CN-105936771-A Graphene printing ink and preparation method thereof 深圳华云科技实业有限公司 2016-09-14 CN disclosed
CN-105907138-A Hard Coating Composition and Hard Coating Film Using the Same 东友精细化工有限公司 2016-08-31 CN disclosed
US-9315451-B2 Tetracycline compounds TETRAPHASE PHARMACEUTICALS, INC. (US) 2016-04-19 US disclosed
US-20120135968-A1 Tetracycline Compounds TETRAPHASE PHARMACEUTICALS, INC. 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170044160-A1 TETRACYCLINE COMPOUNDS TUBB, TUBA1C, TUBA1A MAPT 103/4885RAB9A 1953/4885NPSR1 4283/4885
US-20120135968-A1 Tetracycline Compounds TUBB, TUBA1C, TUBA1A MAPT 103/4885RAB9A 1953/4885NPSR1 4283/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.