Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL9786003 | 0.99 | SLC2A1 (0.40) | SLC2A1TYRADRB2ADORA3CHRM1 | |
| SCHEMBL9786076 | 0.93 | SLC2A1 (0.44) | SLC2A1TYRADRB2ADORA3CHRM1 | |
| Bromide SCHEMBL9786053 | 0.91 | SLC2A1 (0.43) | SLC2A1TYRADRB2ADORA3CHRM1 | |
| Bromide SCHEMBL9786002 | 0.90 | SLC2A1 (0.43) | SLC2A1TYRADRB2ADORA3CHRM1 | |
| Bromide SCHEMBL9786063 | 0.90 | SLC2A1 (0.43) | SLC2A1TYRADRB2ADORA3CHRM1 | |
| Bromide SCHEMBL9786042 | 0.90 | SLC2A1 (0.43) | SLC2A1TYRADRB2ADORA3CHRM1 | |
| Bromide SCHEMBL10872506 | 0.87 | TYR (0.41) | SLC2A1TYRADRB2ADORA3CHRM1 | |
| SCHEMBL7280271 | 0.84 | ADRB2 (0.57) | SLC2A1ADRB2ADORA3CHRM1ADRA2B | |
| Bromide SCHEMBL7280733 | 0.83 | ADRB2 (0.56) | SLC2A1ADRB2ADORA3CHRM1ADRA2B | |
| Bromide SCHEMBL9786026 | 0.83 | SLC2A1 (0.48) | SLC2A1ADRB2ADORA3CHRM1ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0188361-B1 | AMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-03-06 | — | — | EP | claimed |
| EP-0188361-A1 | Amine derivatives | GLAXO GROUP LIMITED (GB) | 1986-07-23 | — | — | EP | claimed |
| US-5023378-A | Hypotensive agents, antiischemic agents, urogenital disorders | GLAXO GROUP LIMITED (GB) | 1991-06-11 | — | — | US | disclosed |
| EP-0188361-B1 | AMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1991-03-06 | — | — | EP | disclosed |
| EP-0188361-A1 | Amine derivatives | GLAXO GROUP LIMITED (GB) | 1986-07-23 | — | — | EP | disclosed |