Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.68 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | TNKS | O95271 | 1/20 | 0.56 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18838242 | 0.89 | HDAC6 (0.55) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL980266 | 0.89 | TNKS (0.56) | HDAC6TNKSKDM4EALDH1A1NPC1 | |
| SCHEMBL5031445 | 0.86 | HDAC6 (0.58) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL21860495 | 0.86 | HDAC6 (0.52) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL5031505 | 0.85 | HDAC6 (0.78) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3981377 | 0.84 | TNKS (0.69) | HDAC6HDAC2TNKSKDM4EALDH1A1 | |
| SCHEMBL9133186 | 0.84 | HDAC6 (0.50) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL977056 | 0.83 | HDAC6 (0.73) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL19029316 | 0.81 | HDAC6 (1.00) | HDAC6HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6485304 | 0.81 | TNKS (0.57) | HDAC6TNKSKDM4EALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250282742-A1 | BENZOFURAN DERIVATIVES FOR TARGETING AUTOPHAGY | Automera PTE. LTD (SG) | 2025-09-11 | — | — | US | disclosed |
| EP-3621957-B1 | FUSED STILBENE DERIVATIVES AS SOLAR CELL DYES | AMBIENT PHOTONICS INC (US) | 2023-08-23 | — | — | EP | disclosed |
| US-20230154691-A1 | Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes | Ambient Photonics, Inc. (US) | 2023-05-18 | — | — | US | disclosed |
| US-20110021540-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 066 | ASTRAZENECA AB (SE) | 2011-01-27 | — | — | US | disclosed |
| EP-2217566-A1 | BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 066 | AstraZeneca AB (SE) | 2010-08-18 | — | — | EP | disclosed |
| US-20090281138-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 066 | ASTRAZENECA AB (SE) | 2009-11-12 | — | — | US | disclosed |
| WO-2009064250-A1 | BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 065 | ASTRAZENECA AB (SE) | 2009-05-22 | — | — | WO | disclosed |
| WO-2009064251-A1 | BIS-(SULFONYLAMINO) DERIVATIVES IN THERAPY 066 | ASTRAZENECA AB (SE) | 2009-05-22 | — | — | WO | disclosed |
| US-20090131468-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 065 | ASTRAZENECA AB (SE) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090131468-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 065 | PTGER1, CYP3A5, SULT1E1 | HDAC6 3409/4885HDAC3 1983/4885HDAC1 2889/4885 |
| US-20090281138-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 066 | CYP2D6, PTGER1, CYP2B6 | HDAC6 3831/4885HDAC3 2511/4885HDAC1 2735/4885 |
| US-20250282742-A1 | BENZOFURAN DERIVATIVES FOR TARGETING AUTOPHAGY | SQSTM1, BECN1, TFEB | HDAC6 39/4885HDAC3 114/4885HDAC1 244/4885 |
| US-20230154691-A1 | Stilbene and Fused Stilbene Derivatives as Solar Cell Dyes | FDFT1, SUN2, CDC73 | HDAC6 4514/4885HDAC3 4278/4885HDAC1 2501/4885 |
| US-20110021540-A1 | Bis-(Sulfonylamino) Derivatives in Therapy 066 | CYP2D6, PTGER1, CYP2B6 | HDAC6 3831/4885HDAC3 2511/4885HDAC1 2735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.