Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786842 | 0.91 | CYP2J2 (0.51) | HRH1KCNH2CYP2J2 | |
| SCHEMBL9786845 | 0.90 | HRH1 (0.52) | HRH1KCNH2CYP2J2 | |
| SCHEMBL9786960 | 0.89 | HRH1 (0.51) | HRH1KCNH2CYP2J2 | |
| SCHEMBL9786898 | 0.89 | HRH1 (0.51) | HRH1KCNH2CYP2J2 | |
| SCHEMBL9786907 | 0.89 | HRH1 (0.51) | HRH1KCNH2CYP2J2 | |
| Water SCHEMBL9786974 | 0.88 | HRH1 (0.50) | HRH1KCNH2CYP2J2 | |
| SCHEMBL9256393 | 0.87 | CYP19A1 (0.49) | CYP19A1HRH1KCNH2 | |
| SCHEMBL9786858 | 0.86 | CYP2J2 (0.58) | HRH1KCNH2CYP2J2 | |
| SCHEMBL7439663 | 0.84 | KCNH2 (0.51) | HRH1KCNH2CYP2J2 | |
| SCHEMBL10569296 | 0.83 | CARM1 (0.54) | CYP19A1HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063235-A | 4-[(diaryl)hydromethyl]-1-piperidinealkanols and esters and carbamates thereof useful in the treatment of allergic disorders | A. H. ROBINS COMPANY, INC. (US) | 1991-11-05 | — | — | US | disclosed |