Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9786852 | 0.87 | CYP19A1 (0.50) | CYP19A1HRH1KCNH2 | |
| SCHEMBL10479209 | 0.85 | HRH1 (0.63) | HRH1KCNH2 | |
| SCHEMBL9786842 | 0.84 | CYP2J2 (0.51) | HRH1KCNH2 | |
| SCHEMBL9873355 | 0.83 | CYP2J2 (0.48) | CYP19A1HRH1KCNH2 | |
| SCHEMBL7439663 | 0.83 | KCNH2 (0.51) | HRH1KCNH2 | |
| SCHEMBL9786845 | 0.83 | HRH1 (0.52) | HRH1KCNH2 | |
| SCHEMBL9873774 | 0.82 | CYP2J2 (0.56) | HRH1KCNH2 | |
| SCHEMBL9786898 | 0.82 | HRH1 (0.51) | HRH1KCNH2 | |
| SCHEMBL9786960 | 0.82 | HRH1 (0.51) | HRH1KCNH2 | |
| SCHEMBL9786907 | 0.82 | HRH1 (0.51) | HRH1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470851-A | Antihistamine, anticoagulants | SANKYO COMPANY, LIMITED (JP) | 1995-11-28 | — | — | US | disclosed |
| EP-0463873-A1 | Thiazolidinecarboxylic acid amide derivatives having anti-allergic activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-01-02 | — | — | EP | disclosed |