Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 5/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 5/20 | 0.54 |
| ▸ | HRH1 | P35367 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10568072 | 0.86 | HRH1 (0.62) | CARM1PRMT6HRH1KCNH2 | |
| SCHEMBL9786852 | 0.83 | CYP19A1 (0.50) | HRH1CYP19A1KCNH2 | |
| SCHEMBL9873976 | 0.82 | CYP2J2 (0.48) | — | |
| SCHEMBL9256393 | 0.82 | CYP19A1 (0.49) | HRH1CYP19A1KCNH2 | |
| SCHEMBL9786842 | 0.81 | CYP2J2 (0.51) | HRH1KCNH2 | |
| SCHEMBL9786980 | 0.80 | HRH1 (0.44) | HRH1KCNH2 | |
| SCHEMBL9874649 | 0.80 | CYP2J2 (0.54) | HRH1KCNH2 | |
| SCHEMBL7439663 | 0.80 | KCNH2 (0.51) | HRH1KCNH2 | |
| SCHEMBL9786845 | 0.80 | HRH1 (0.52) | HRH1KCNH2 | |
| SCHEMBL14198330 | 0.79 | CYP19A1 (0.55) | HRH1CYP19A1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4853387-A | Piperidine derivatives, and their application in therapy | SYNTHELABO (FR) | 1989-08-01 | — | — | US | disclosed |