Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | RARA | P10276 | 1/20 | 0.37 |
| ▸ | RARB | P10826 | 1/20 | 0.37 |
| ▸ | RARG | P13631 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11989399 | 0.78 | ALDH1A1 (0.51) | ADRB2ALDH1A1HTTPOLB | |
| SCHEMBL5461374 | 0.76 | ADRB2 (0.55) | ADRB2ALDH1A1HTTNR4A1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28672479 | 0.75 | ALDH1A1 (0.47) | ADRB2ALDH1A1KMT2ARXRARXRB | |
| SCHEMBL3618445 | 0.73 | ADRB2 (0.65) | ADRB2ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL8125084 | 0.72 | ALDH1A1 (0.46) | ADRB2ALDH1A1HTTKMT2AMEN1 | |
| SCHEMBL7505931 | 0.72 | ADRB2 (0.59) | ADRB2ALDH1A1HTTSMN1; SMN2CTSK | |
| SCHEMBL20069529 | 0.71 | ALDH1A1 (0.45) | ADRB2ALDH1A1HTTP2RX7POLB | |
| SCHEMBL4634362 | 0.70 | CNR2 (0.41) | ADRB2ALDH1A1HTT | |
| SCHEMBL5807513 | 0.70 | HTT (0.41) | ADRB2ALDH1A1HTTKDM4EGAA | |
| Hydrochloric Acid SCHEMBL5811140 | 0.69 | CNR2 (0.40) | ADRB2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4689182-A | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-08-25 | — | — | US | claimed |
| EP-0226223-A2 | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-06-24 | — | — | EP | claimed |
| US-5002703-A | Benzoic acid and benzoic acid ester derivatives having antiinflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1991-03-26 | — | — | US | disclosed |
| US-4990533-A | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT CO. (US) | 1991-02-05 | — | — | US | disclosed |
| US-4980095-A | Sodium salt of N-C4-carboxybenzyl nonanamide | WARNER-LAMBERT COMPANY (US) | 1990-12-25 | — | — | US | disclosed |
| US-4771064-A | Benzoic acid and benzoic acid ester derivatives having antiflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| US-4755518-A | Imidazolyl or tetrazolyl substituted benzoic acid derivatives and pharmaceutical compositions thereof | WARNER-LAMBERT COMPANY (US) | 1988-07-05 | — | — | US | disclosed |
| US-4719232-A | Benzoic acid and benzoic acid ester derivatives to treat headaches | WARNER-LAMBERT COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719234-A | Benzoic acid and benzoic acid ester derivatives to treat inflammation | WARNER-LAMBERT COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4719233-A | Benzoic acid and benzoic acid ester derivatives to treat pain | WARNER-LAMBERT COMPANY (US) | 1988-01-12 | — | — | US | disclosed |
| US-4689182-A | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-08-25 | — | — | US | disclosed |
| EP-0226223-A2 | Benzoic acid and benzoic acid ester derivatives having anti-inflammatory and analgesic activity | WARNER-LAMBERT COMPANY (US) | 1987-06-24 | — | — | EP | disclosed |