Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787605 | 0.95 | LMNA (0.32) | LMNAKDM4EGMNNUSP2ALDH1A1 | |
| SCHEMBL9787543 | 0.84 | LMNA (0.35) | LMNAKDM4EGMNNUSP2ALDH1A1 | |
| SCHEMBL9787544 | 0.84 | LMNA (0.35) | LMNAKDM4EGMNNUSP2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9787533 | 0.82 | LMNA (0.34) | LMNAKDM4EGMNNUSP2ALDH1A1 | |
| SCHEMBL9787658 | 0.82 | LMNA (0.34) | LMNAKDM4EGMNNUSP2ALDH1A1 | |
| SCHEMBL4587818 | 0.81 | TPMT (0.41) | LMNAKDM4EALDH1A1TP53CYP1A2 | |
| SCHEMBL5805414 | 0.79 | LMNA (0.38) | LMNAKDM4EGMNNUSP2ALDH1A1 | |
| SCHEMBL11387992 | 0.79 | TSHR (0.40) | LMNAALDH1A1HPGDSMN1; SMN2TSHR | |
| Monoethanolamine SCHEMBL9787617 | 0.78 | TSHR (0.38) | LMNAALDH1A1BLMSMN1; SMN2TPMT | |
| Hydrochloric Acid SCHEMBL9787611 | 0.78 | TPMT (0.39) | LMNATP53CYP1A2TPMTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5047228-A | X-ray contrast; medical diagnosis | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-09-10 | — | — | US | disclosed |