Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.34 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.34 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22645201 | 0.90 | TSHR (0.46) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL11394886 | 0.89 | TSHR (0.45) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11147542 | 0.87 | TSHR (0.42) | TSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL11391686 | 0.84 | SMN1; SMN2 (0.41) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8727104 | 0.81 | TSHR (0.47) | TSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9787580 | 0.79 | LMNA (0.35) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL11387512 | 0.78 | TSHR (0.47) | TSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL11401032 | 0.77 | LMNA (0.37) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL22661229 | 0.77 | TSHR (0.39) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL8743099 | 0.76 | ALDH1A1 (0.40) | TSHRMAPK1LMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4283381-A | OPAQUING AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 1981-08-11 | — | — | US | disclosed |