Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 10/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787693 | 0.84 | MMP1 (0.55) | CAPN1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL20168642 | 0.78 | SLC6A4 (0.53) | CAPN1SLC6A4 | |
| SCHEMBL20168641 | 0.78 | SLC6A4 (0.53) | CAPN1SLC6A4 | |
| SCHEMBL26073693 | 0.75 | SLC6A4 (0.53) | SLC6A4TDP1 | |
| SCHEMBL5806608 | 0.74 | SLC6A4 (0.54) | SLC6A4TDP1 | |
| SCHEMBL6229483 | 0.74 | SLC6A4 (0.41) | SLC6A4TDP1 | |
| SCHEMBL26073698 | 0.74 | KMT2A (0.61) | SLC6A4NPBWR1TDP1 | |
| SCHEMBL9787708 | 0.72 | IL1RN (0.50) | — | |
| SCHEMBL30052459 | 0.72 | ECE1 (0.61) | MMP1 | |
| SCHEMBL1237981 | 0.71 | IL1RN (0.67) | MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997950-A | Antisecretory | MURPHY RICHARD FINBAR (US) | 1991-03-05 | — | — | US | disclosed |