Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | NMBR | P28336 | 5/20 | 0.51 |
| ▸ | CA12 | O43570 | 3/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | CA9 | Q16790 | 3/20 | 0.50 |
| ▸ | TACR3 | P29371 | 1/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | BRS3 | P32247 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20168641 | 1.00 | SLC6A4 (0.53) | SLC6A4NMBRCA12CA1CA2 | |
| SCHEMBL20182251 | 0.91 | TRPV1 (0.47) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL20168529 | 0.91 | TRPV1 (0.47) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL20168527 | 0.91 | TRPV1 (0.47) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL5806608 | 0.89 | SLC6A4 (0.54) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL26073693 | 0.88 | SLC6A4 (0.53) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL9787693 | 0.88 | MMP1 (0.55) | SLC6A4MEN1KMT2ACAPN1 | |
| SCHEMBL26073698 | 0.87 | KMT2A (0.61) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL17468007 | 0.83 | SLC6A4 (0.51) | SLC6A4CA12CA1CA2CA9 | |
| SCHEMBL17243945 | 0.82 | SLC6A4 (0.47) | SLC6A4CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12570606-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2026-03-10 | — | — | US | disclosed |
| EP-3541431-B1 | MYELOPEROXIDASE IMAGING AGENTS | MASSACHUSETTS GEN HOSPITAL (US) | 2024-04-17 | — | — | EP | disclosed |
| US-20220340524-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2022-10-27 | — | — | US | disclosed |
| US-11352326-B2 | Myeloperoxidase imaging agents | THE GENERAL HOSPITAL CORPORATION (US) | 2022-06-07 | — | — | US | disclosed |
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | THE GENERAL HOSPITAL CORPORATION | 2019-10-17 | — | — | US | disclosed |
| EP-3541431-A1 | MYELOPEROXIDASE IMAGING AGENTS | The General Hospital Corporation (US) | 2019-09-25 | — | — | EP | disclosed |
| WO-2018094005-A1 | MYELOPEROXIDASE IMAGING AGENTS | THE GENERAL HOSPITAL CORPORATION (US) | 2018-05-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220340524-A1 | Myeloperoxidase Imaging Agents | MPO, CAT, EPX | SLC6A4 3021/4885NMBR 1603/4885CA12 1110/4885 |
| US-12570606-B2 | Myeloperoxidase imaging agents | MPO, CBR1, NOX1 | SLC6A4 3147/4885NMBR 1041/4885CA12 298/4885 |
| US-20190315689-A1 | Myeloperoxidase Imaging Agents | MPO, CAT, EPX | SLC6A4 1782/4885NMBR 889/4885CA12 936/4885 |
| US-11352326-B2 | Myeloperoxidase imaging agents | MPO, CAT, EPX | SLC6A4 1782/4885NMBR 889/4885CA12 936/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.