Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 12/20 | 0.52 |
| ▸ | CTSK | P43235 | 10/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | CTSB | P07858 | 2/20 | 0.52 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.52 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22498641 | 1.00 | CTSS (0.52) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL29844099 | 0.89 | CAPN1 (0.52) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL25206530 | 0.87 | CTSS (0.54) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL9787700 | 0.87 | CTSS (0.69) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL25206531 | 0.87 | CTSS (0.54) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL22507116 | 0.87 | CTSS (0.57) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL4653243 | 0.85 | MEN1 (0.57) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL9226653 | 0.84 | CTSS (0.50) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL4885990 | 0.84 | CTSS (0.52) | CTSSCTSKCTSLCTSBCAPN1 | |
| SCHEMBL16909018 | 0.84 | SIRT5 (0.57) | CTSSCTSKCAPN1SIRT5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3946363-A2 | GLUCOSE SENSITIVE INSULIN DERIVATIVES | Novo Nordisk A/S (DK) | 2022-02-09 | — | — | EP | disclosed |
| CN-113646329-A | Glucose-sensitive insulin derivatives | 诺和诺德股份有限公司 | 2021-11-12 | — | — | CN | disclosed |
| WO-2020201041-A2 | GLUCOSE SENSITIVE INSULIN DERIVATIVES | NOVO NORDISK A/S (DK) | 2020-10-08 | — | — | WO | disclosed |