Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MT-CO2 | P00403 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | F13A1 | P00488 | 1/20 | 0.54 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | ESRRG | P62508 | 1/20 | 0.51 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL167922 | 0.91 | NPC1 (0.63) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11684013 | 0.83 | DNMT3A (0.65) | MT-CO2DNMT3AALDH1A1NPC1RAB9A | |
| SCHEMBL18216871 | 0.80 | HCRTR1 (0.56) | KDM4EALDH1A1PTGS2MEN1KMT2A | |
| SCHEMBL14264608 | 0.79 | HCRTR1 (0.55) | KDM4EALDH1A1PTGS2MEN1KMT2A | |
| SCHEMBL9787710 | 0.78 | SMN1; SMN2 (0.49) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13097974 | 0.78 | NPSR1 (0.64) | KDM4EALDH1A1PTGS2MEN1KMT2A | |
| SCHEMBL5943342 | 0.78 | HCRTR1 (0.58) | KDM4EALDH1A1PTGS2MEN1KMT2A | |
| SCHEMBL1799221 | 0.77 | PTGS2 (0.59) | KDM4EALDH1A1PTGS2MEN1KMT2A | |
| SCHEMBL13320225 | 0.77 | HSD17B10 (0.59) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28669460 | 0.77 | NPC1 (0.58) | ALDH1A1NPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |