Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | ESRRG | P62508 | 1/20 | 0.43 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | FABP2 | P12104 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9787705 | 0.86 | SMN1; SMN2 (0.45) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL167922 | 0.79 | NPC1 (0.63) | SMN1; SMN2NPC1RAB9APTGS2ALDH1A1 | |
| SCHEMBL9787782 | 0.78 | MT-CO2 (0.56) | SMN1; SMN2NPC1RAB9APTGS2ALDH1A1 | |
| SCHEMBL11682489 | 0.70 | KDM4E (0.64) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL18216871 | 0.70 | HCRTR1 (0.56) | PTGS2ALDH1A1KMT2AKDM4EMAPT | |
| SCHEMBL1799221 | 0.70 | PTGS2 (0.59) | PTGS2ALDH1A1KMT2AKDM4EHCRTR1 | |
| SCHEMBL11686019 | 0.69 | MAPT (0.50) | SMN1; SMN2NPC1RAB9AALDH1A1KMT2A | |
| SCHEMBL14264608 | 0.69 | HCRTR1 (0.55) | PTGS2ALDH1A1KMT2AKDM4EHCRTR1 | |
| SCHEMBL11327533 | 0.68 | NAAA (0.63) | PTGS2ALDH1A1KMT2AHCRTR1MEN1 | |
| SCHEMBL5943342 | 0.68 | HCRTR1 (0.58) | PTGS2ALDH1A1KMT2AKDM4EHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |