Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.44 |
| ▸ | LTA4H | P09960 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL9787776 | 0.94 | ADRB3 (0.51) | ADRB3KDM4EGAASMN1; SMN2TDP1 | |
| SCHEMBL9787809 | 0.89 | ADRB3 (0.51) | ADRB3MEN1KMT2AADRB1 | |
| Oxalic Acid SCHEMBL9787778 | 0.87 | ADRB3 (0.55) | ADRB3KDM4EGAASMN1; SMN2TDP1 | |
| SCHEMBL9494415 | 0.86 | ADRB3 (0.53) | ADRB3KDM4EGAASMN1; SMN2TDP1 | |
| SCHEMBL9494401 | 0.86 | ADRB3 (0.53) | ADRB3KDM4EGAASMN1; SMN2TDP1 | |
| Alcohol SCHEMBL9787806 | 0.86 | ADRB3 (0.50) | ADRB3ADRB1 | |
| SCHEMBL9787723 | 0.83 | ACACB (0.51) | ADRB3MEN1KMT2AADRB1ADRB2 | |
| SCHEMBL9787801 | 0.80 | ADRB3 (0.51) | ADRB3KDM4EGAASMN1; SMN2TDP1 | |
| Oxalic Acid SCHEMBL9787807 | 0.78 | ADRB3 (0.54) | ADRB3KDM4EGAASMN1; SMN2TDP1 | |
| Alcohol SCHEMBL9787714 | 0.78 | ACACB (0.48) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |