Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 9/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9494415 | 1.00 | ADRB3 (0.53) | ADRB3GAASMN1; SMN2KDM4ETDP1 | |
| Oxalic Acid SCHEMBL9787778 | 0.96 | ADRB3 (0.55) | ADRB3GAASMN1; SMN2KDM4ETDP1 | |
| Oxalic Acid SCHEMBL9787807 | 0.86 | ADRB3 (0.54) | ADRB3GAASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL9787784 | 0.86 | ADRB3 (0.54) | ADRB3GAASMN1; SMN2KDM4ETDP1 | |
| Oxalic Acid SCHEMBL9787785 | 0.85 | ADRB3 (0.47) | ADRB3GAASMN1; SMN2KDM4ETDP1 | |
| Alcohol SCHEMBL9787776 | 0.85 | ADRB3 (0.51) | ADRB3GAASMN1; SMN2KDM4ETDP1 | |
| Oxalic Acid SCHEMBL9787821 | 0.84 | ADRB3 (0.45) | ADRB3GAASMN1; SMN2KDM4ETDP1 | |
| Oxalic Acid SCHEMBL9787744 | 0.83 | KDM4E (0.48) | ADRB3GAASMN1; SMN2KDM4ETDP1 | |
| Oxalic Acid SCHEMBL9787715 | 0.83 | ADRB3 (0.49) | ADRB3GAASMN1; SMN2KDM4ETDP1 | |
| SCHEMBL9492908 | 0.83 | ADRB3 (0.42) | ADRB3SMN1; SMN2TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345591-B1 | PROPANOL AMINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1993-03-31 | — | — | EP | claimed |
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |