Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 12/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 9/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9787778 | 0.90 | ADRB3 (0.55) | ADRB3SMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL9494415 | 0.85 | ADRB3 (0.53) | ADRB3ADRB2SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9494401 | 0.85 | ADRB3 (0.53) | ADRB3ADRB2SMN1; SMN2MEN1KMT2A | |
| Oxalic Acid SCHEMBL9787807 | 0.84 | ADRB3 (0.54) | ADRB3ADRB1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL9782146 | 0.84 | ADRB1 (0.58) | ADRB3ADRB1ADRB2 | |
| Oxalic Acid SCHEMBL9787715 | 0.83 | ADRB3 (0.49) | ADRB3ADRB1SMN1; SMN2MEN1KMT2A | |
| Oxalic Acid SCHEMBL9787821 | 0.82 | ADRB3 (0.45) | ADRB3ADRB1ADRB2SMN1; SMN2MEN1 | |
| Oxalic Acid SCHEMBL9787744 | 0.81 | KDM4E (0.48) | ADRB3ADRB1SMN1; SMN2MEN1KMT2A | |
| Oxalic Acid SCHEMBL9787761 | 0.80 | ADRB3 (0.45) | ADRB3ADRB1ADRB2SMN1; SMN2MEN1 | |
| Alcohol SCHEMBL9787776 | 0.78 | ADRB3 (0.51) | ADRB3ADRB1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5045567-A | Propanolamine derivatives having anti-diabetic effects | HOFFMANN-LA ROCHE INC. (US) | 1991-09-03 | — | — | US | disclosed |