Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 4/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474113 | 1.00 | LPL (0.33) | LPLLIPGKCNH2KDM4EPDE3B | |
| SCHEMBL9787852 | 1.00 | LPL (0.33) | LPLLIPGKCNH2KDM4EPDE3B | |
| SCHEMBL10619634 | 1.00 | LPL (0.33) | LPLLIPGKCNH2KDM4EPDE3B | |
| SCHEMBL10616726 | 1.00 | LPL (0.33) | LPLLIPGKCNH2KDM4EPDE3B | |
| SCHEMBL9787882 | 1.00 | LPL (0.33) | LPLLIPGKCNH2KDM4EPDE3B | |
| SCHEMBL10491866 | 1.00 | LPL (0.33) | LPLLIPGKCNH2KDM4EPDE3B | |
| SCHEMBL9787850 | 1.00 | LPL (0.33) | LPLLIPGKCNH2KDM4EPDE3B | |
| SCHEMBL10491816 | 1.00 | LPL (0.33) | LPLLIPGKCNH2KDM4EPDE3B | |
| SCHEMBL9787963 | 0.98 | KDM4E (0.34) | LPLLIPGKCNH2KDM4E | |
| SCHEMBL5796273 | 0.92 | KDM4E (0.35) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5030629-A | Transdermal Administration Of Cardiovascular Agents | THERAPEUTIC PATCH RESEARCH N.V. | 1991-07-09 | — | — | US | disclosed |
| US-4876249-A | TOPICAL; TRANSDERMAL, SYSTEMIC; FLUOCINOLINE ACETONIDE AND IMIDAZOLINE OR OXAZOLINE PENETRATION ENHANCER MIXTURE; THERAPEUTIC DRUGS | THERAPEUTIC PATCH RESEARCH N.V. | 1989-10-24 | — | — | US | disclosed |