SCHEMBL474113

SCHEMBL474113

CCCCCCCCCCCC1=NC(C)(C)CO1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPL P06858 4/20 0.33
LIPG Q9Y5X9 4/20 0.33
KCNH2 Q12809 1/20 0.33
KDM4E B2RXH2 1/20 0.33
PDE3B Q13370 1/20 0.32
PDE3A Q14432 1/20 0.32
TSHR P16473 1/20 0.31
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9787852 1.00 LPL (0.33) LPLLIPGKCNH2KDM4EPDE3B
SCHEMBL9788005 1.00 LPL (0.33) LPLLIPGKCNH2KDM4EPDE3B
SCHEMBL10619634 1.00 LPL (0.33) LPLLIPGKCNH2KDM4EPDE3B
SCHEMBL10616726 1.00 LPL (0.33) LPLLIPGKCNH2KDM4EPDE3B
SCHEMBL9787882 1.00 LPL (0.33) LPLLIPGKCNH2KDM4EPDE3B
SCHEMBL10491866 1.00 LPL (0.33) LPLLIPGKCNH2KDM4EPDE3B
SCHEMBL9787850 1.00 LPL (0.33) LPLLIPGKCNH2KDM4EPDE3B
SCHEMBL10491816 1.00 LPL (0.33) LPLLIPGKCNH2KDM4EPDE3B
SCHEMBL9787963 0.98 KDM4E (0.34) LPLLIPGKCNH2KDM4E
SCHEMBL5796273 0.92 KDM4E (0.35) KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 318 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12544361-B2 Composition comprising at least one oxazoline for inhibiting the growth of Malassezia yeasts involved in cradle cap, in particular LABORATOIRES EXPANSCIENCE (FR) 2026-02-10 US claimed
US-20220249446-A1 Composition Comprising at Least One Oxazoline for Inhibiting the Growth of Malassezia Yeasts Involved in Cradle Cap, in Particular LABORATOIRES EXPANSCIENCE (FR) 2022-08-11 US claimed
EP-3996674-A1 COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE FOR INHIBITING THE GROWTH OF MALASSEZIA YEASTS INVOLVED IN CRADLE CAP, IN PARTICULAR Laboratoires Expanscience (FR) 2022-05-18 EP claimed
EP-2953611-B1 USE OF A COMPOSITION COMPRISING AVOCADO PERSEOSE IN THE PROTECTION OF EPIDERMAL STEM CELLS EXPANSCIENCE LAB (FR) 2021-08-18 EP claimed
WO-2021009142-A1 COMPOSITION COMPRISING AT LEAST ONE OXAZOLINE FOR INHIBITING THE GROWTH OF MALASSEZIA YEASTS INVOLVED IN CRADLE CAP, IN PARTICULAR LABORATOIRES EXPANSCIENCE (FR) 2021-01-21 WO claimed
US-20200085897-A1 Extract of Aerial Parts of Maca Rich in Polyphenols and Composition Comprising Same LABORATOIRES EXPANSCIENCE (FR) 2020-03-19 US claimed
EP-2654765-B1 EXTRACT OF THE AERIAL PARTS OF MACA RICH IN POLYPHENOL AND COMPOSITION COMPRISING THE EXTRACT EXPANSCIENCE LAB (FR) 2019-03-13 EP claimed
EP-2654766-B1 EXTRACT OF THE PULP AND/OR PEEL OF AVOCADO RICH IN POLYPHENOLS AND COSMETIC, DERMATOLOGIC OR NUTRACEUTIC COMPOSITIONS COMPRISING THEREOF EXPANSCIENCE LAB (FR) 2018-10-10 EP claimed
EP-2654762-B1 EXTRACT OF THE AERIAL PARTS OF GYNANDROPSIS GYNANDRA AND COSMETIC, DERMATOLIGIC AND PHARMACEUTIC COMPOSITIONS COMPRISING THE EXTRACT EXPANSCIENCE LAB (FR) 2018-09-26 EP claimed
US-9616009-B2 Composition containing at least one C7 sugar for alopecia treatment, cosmetic treatment of hair and nails, and care of hair, eyelashes or nails LABORATOIRES EXPANSCIENCE (FR) 2017-04-11 US claimed
WO-2004112741-A1 COSMETIC USE OF A COMPOSITION CONTAINING AT LEAST ONE OXAZOLINE, SERVING AS AN ACTIVE SUBSTANCE, AS A SLIMMING PRODUCT AND/OR FOR PREVENTING AND/OR TREATING CELLULITE LABORATOIRES EXPANSCIENCE (FR) 2004-12-29 WO claimed
EP-1458349-A1 COMPOSITION COMPRISING AT LEAST AN OXAZOLIN FOR INHIBITING LANGERHANS CELL MIGRATION, AND USES THEREOF Laboratoires Expanscience (FR) 2004-09-22 EP claimed
WO-2003055463-A1 COMPOSITION COMPRISING AT LEAST AN OXAZOLIN FOR INHIBITING LANGERHANS CELL MIGRATION, AND USES THEREOF LABORATOIRES EXPANSCIENCE (FR) 2003-07-10 WO claimed
EP-0260339-B1 OXAZOLINE/POLYOL/POLYISOCYANATE POLYMERS AND PROCESS Ashland Oil, Inc. (US) 1991-03-13 EP claimed
US-4876249-A TOPICAL; TRANSDERMAL, SYSTEMIC; FLUOCINOLINE ACETONIDE AND IMIDAZOLINE OR OXAZOLINE PENETRATION ENHANCER MIXTURE; THERAPEUTIC DRUGS THERAPEUTIC PATCH RESEARCH N.V. 1989-10-24 US claimed
EP-0296199-A1 HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE RAJADHYAKSHA, Vithal J. (US) 1988-12-28 EP claimed
WO-1988004938-A1 HETEROCYCLIC COMPOUNDS FOR TRANSDERMAL USE RAJADHYAKSHA VITHAL J (US) 1988-07-14 WO claimed
EP-0260339-A1 Oxazoline/polyol/polyisocyanate polymers and process Ashland Oil, Inc. (US) 1988-03-23 EP claimed
US-4640969-A IMPROVED IMPACT STRENGHT ASHLAND OIL, INC. (US) 1987-02-03 US claimed
US-4558114-A INCREASING REACTION RATES ASHLAND OIL, INC. (US) 1985-12-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12544361-B2 Composition comprising at least one oxazoline for inhibiting the growth of Malassezia yeasts involved in cradle cap, in particular HSD17B12, CYP51A1, OXGR1 LPL 2826/4885LIPG 1713/4885KCNH2 4512/4885
US-20220249446-A1 Composition Comprising at Least One Oxazoline for Inhibiting the Growth of Malassezia Yeasts Involved in Cradle Cap, in Particular OCIAD1, ERG28, CYP51A1 LPL 3196/4885LIPG 1796/4885KCNH2 4055/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.