Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
| ▸ | MMP3 | P08254 | 2/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7156294 | 0.74 | TSHR (0.42) | ANPEPALDH1A1TSHRMAPK1 | |
| SCHEMBL9219324 | 0.74 | ANPEP (0.43) | ANPEPERAP2ERAP1RNPEPALDH1A1 | |
| SCHEMBL9211509 | 0.72 | ANPEP (0.37) | ANPEPERAP2ERAP1RNPEPALDH1A1 | |
| SCHEMBL4004788 | 0.71 | — | — | |
| SCHEMBL8387385 | 0.71 | — | — | |
| SCHEMBL28745209 | 0.70 | ALDH1A1 (0.35) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL9207635 | 0.67 | — | — | |
| SCHEMBL14840489 | 0.65 | TSHR (0.47) | ANPEPERAP2ERAP1ALDH1A1TSHR | |
| SCHEMBL154444 | 0.64 | — | — | |
| SCHEMBL14220458 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4985582-A | CHEMICAL INTERMEDIATES FOR BICYCLIC RING COMPOUNDS HAVING MULTIPLE SULFUR ATOMS IN THE RING SYSTEM | THE WELLCOME FOUNDATION LTD. (GB) | 1991-01-15 | — | — | US | disclosed |
| EP-0216625-A2 | Pesticidal compounds | THE WELLCOME FOUNDATION LIMITED (GB) | 1987-04-01 | — | — | EP | disclosed |