SCHEMBL7156294

SCHEMBL7156294

CCC(CC(C)C)C(O)O

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.42
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.32
MAPK1 P28482 1/20 0.32
ANPEP P15144 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3228663 0.80 TSHR (0.40) TSHRLMNA
SCHEMBL320579 0.77
SCHEMBL27757358 0.77 TSHR (0.35) TSHRLMNA
SCHEMBL599070 0.75 TSHR (0.35) TSHRALDH1A1MAPK1
SCHEMBL1614311 0.74 LMNA (0.42) TSHRLMNAALDH1A1MAPK1
SCHEMBL9788178 0.74 ANPEP (0.42) TSHRALDH1A1MAPK1ANPEP
SCHEMBL17464917 0.74 LMNA (0.42) TSHRLMNAALDH1A1MAPK1
SCHEMBL11280505 0.74 TSHR (0.35) TSHR
SCHEMBL11533508 0.73 TSHR (0.33) TSHRALDH1A1MAPK1
SCHEMBL12812805 0.72 TSHR (0.33) TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1027315-B1 PROCESS FOR THE PRODUCTION OF N-BUTANOL CELANESE INT CORP (US) 2003-06-04 EP disclosed
EP-1027315-A1 PROCESS FOR THE PRODUCTION OF N-BUTANOL Celanese International Corporation (US) 2000-08-16 EP disclosed
US-5922921-A CONTACTING N-BUTYRALDEHYDE AND HYDROGEN WITH ACTIVE POROUS COBALT CATALYST IN HYDROGENATION ZONE, PURIFYING BY FRACTIONAL DISTILLATION CELANESE INTERNATIONAL CORPORATION (US) 1999-07-13 US disclosed
WO-1999021812-A1 PROCESS FOR THE PRODUCTION OF N-BUTANOL CELANESE INTERNATIONAL CORPORATION (US) 1999-05-06 WO disclosed