SCHEMBL9788223

SCHEMBL9788223

CC(N)C(O)CCN(C)Cc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 1/20 0.59
PRMT6 Q96LA8 1/20 0.59
PRMT8 Q9NR22 1/20 0.59
SIGMAR1 Q99720 1/20 0.46
AOC3 Q16853 1/20 0.43
ALDH1A1 P00352 3/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
KDM4E B2RXH2 2/20 0.42
TSHR P16473 3/20 0.41
MAOB P27338 2/20 0.41
ADRA2B P18089 1/20 0.41
ADRA2C P18825 1/20 0.41
SLC6A2 P23975 1/20 0.41
HTR2A P28223 1/20 0.41
SLC6A4 P31645 1/20 0.41
ADRA1A P35348 1/20 0.41
OPRK1 P41145 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KCNH2 Q12809 1/20 0.41
USP2 O75604 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4798287 0.87 CARM1 (0.53) CARM1PRMT6PRMT8SIGMAR1ALDH1A1
SCHEMBL19746594 0.83 CARM1 (0.56) CARM1PRMT6PRMT8SIGMAR1ALDH1A1
SCHEMBL23278222 0.83 CARM1 (0.61) CARM1PRMT6PRMT8SIGMAR1AOC3
SCHEMBL5478551 0.83 CARM1 (0.56) CARM1PRMT6PRMT8SIGMAR1ALDH1A1
SCHEMBL14578374 0.79 CARM1 (0.60) CARM1PRMT6PRMT8SIGMAR1AOC3
SCHEMBL4802584 0.77 CARM1 (0.50) CARM1PRMT6PRMT8SIGMAR1ALDH1A1
SCHEMBL5482899 0.77 CARM1 (0.50) CARM1PRMT6PRMT8SIGMAR1ALDH1A1
SCHEMBL8399769 0.77 SIGMAR1 (0.57) CARM1PRMT6PRMT8SIGMAR1MAOB
SCHEMBL18732997 0.77 CARM1 (0.58) CARM1PRMT6PRMT8SIGMAR1AOC3
SCHEMBL4852041 0.77 CARM1 (0.53) CARM1PRMT6PRMT8SIGMAR1AOC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5006621-A Co-polymers of long chain alkyl acrylates with N-containing olefins and their use as flow improvers for crude oils HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1991-04-09 US disclosed