Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 12/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 10/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.37 |
| ▸ | CFB | P00751 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788292 | 0.89 | TAAR1 (0.42) | TAAR1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL9788321 | 0.79 | TAAR1 (0.48) | TAAR1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL7048853 | 0.77 | TAAR1 (0.52) | TAAR1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL7043901 | 0.77 | TAAR1 (0.43) | TAAR1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL9788294 | 0.75 | ADRA2A (0.40) | TAAR1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL9788281 | 0.75 | ADRA2A (0.40) | TAAR1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL9788325 | 0.74 | ADRA2A (0.40) | TAAR1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL9788279 | 0.72 | TAAR1 (0.41) | TAAR1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL7045608 | 0.71 | TAAR1 (0.46) | TAAR1ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL10959530 | 0.70 | IDO1 (0.46) | RETGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066664-A | Control of intraocular bleeding and pressure | ALLERGAN, INC. (US) | 1991-11-19 | — | — | US | disclosed |