Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | CFB | P00751 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 11/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 8/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 8/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 8/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | KIF5B | P33176 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788328 | 0.86 | ADRA2A (0.45) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL7046036 | 0.84 | TAAR1 (0.57) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL9788292 | 0.81 | TAAR1 (0.42) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL7045608 | 0.79 | TAAR1 (0.46) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL9788302 | 0.79 | TAAR1 (0.40) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL9788263 | 0.79 | CFB (0.41) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL9788291 | 0.79 | TAAR1 (0.45) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL7047648 | 0.78 | TAAR1 (0.56) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL9788294 | 0.77 | ADRA2A (0.40) | TAAR1CFBADRA2AADRA1AADRA2B | |
| SCHEMBL9788281 | 0.77 | ADRA2A (0.40) | TAAR1CFBADRA2AADRA1AADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066664-A | Control of intraocular bleeding and pressure | ALLERGAN, INC. (US) | 1991-11-19 | — | — | US | disclosed |