Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 7/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 6/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.36 |
| ▸ | CFB | P00751 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 5/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788287 | 0.89 | CFB (0.40) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL9788300 | 0.89 | CFB (0.40) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL9788271 | 0.82 | TNIK (0.45) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL9788288 | 0.75 | CFB (0.38) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL9788341 | 0.75 | CFB (0.38) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL9788289 | 0.75 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL9788292 | 0.73 | TAAR1 (0.42) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL9788276 | 0.72 | CFB (0.46) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL9788343 | 0.72 | TAAR1 (0.44) | ADRA2AADRA2BADRA2CADRA1ACFB | |
| SCHEMBL9788281 | 0.72 | ADRA2A (0.40) | ADRA2AADRA2BADRA2CADRA1ACFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066664-A | Control of intraocular bleeding and pressure | ALLERGAN, INC. (US) | 1991-11-19 | — | — | US | disclosed |