Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 13/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.41 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.41 |
| ▸ | CFB | P00751 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9788325 | 0.89 | ADRA2A (0.40) | TNIKADRA2AADRA1AADRA2BADRA2C | |
| SCHEMBL9788339 | 0.82 | ADRA2A (0.36) | ADRA2AADRA1AADRA2BADRA2CCFB | |
| SCHEMBL9788340 | 0.81 | CFB (0.50) | TNIKADRA2AADRA1AADRA2BADRA2C | |
| SCHEMBL9788289 | 0.80 | ADRA2A (0.40) | ADRA2AADRA1AADRA2BADRA2CCFB | |
| SCHEMBL9788300 | 0.80 | CFB (0.40) | ADRA2AADRA1AADRA2BADRA2CCFB | |
| SCHEMBL9788276 | 0.80 | CFB (0.46) | TNIKADRA2AADRA1AADRA2BADRA2C | |
| SCHEMBL9788287 | 0.77 | CFB (0.40) | ADRA2AADRA1AADRA2BADRA2CCFB | |
| SCHEMBL9788343 | 0.74 | TAAR1 (0.44) | ADRA2AADRA1AADRA2BADRA2CCFB | |
| SCHEMBL9788281 | 0.74 | ADRA2A (0.40) | ADRA2AADRA1AADRA2BADRA2CCFB | |
| SCHEMBL9788294 | 0.74 | ADRA2A (0.40) | ADRA2AADRA1AADRA2BADRA2CCFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5066664-A | Control of intraocular bleeding and pressure | ALLERGAN, INC. (US) | 1991-11-19 | — | — | US | disclosed |