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SCHEMBL9788346

SCHEMBL9788346

CC(NC(=O)CNC(=O)C1(C)CC1(Cl)Cl)c1ccc(Cl)cc1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GPR139 Q6DWJ6 8/20 0.54
▸ MEN1 O00255 2/20 0.46
▸ KMT2A Q03164 2/20 0.46
▸ ATM Q13315 1/20 0.46
▸ HPGD P15428 2/20 0.45
▸ GAA P10253 1/20 0.44
▸ SMN1; SMN2 Q16637 1/20 0.44
▸ PRCP P42785 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9788348 0.86 GPR139 (0.53) GPR139MEN1KMT2AATMHPGD
SCHEMBL9788334 0.79 MEN1 (0.53) MEN1KMT2AHPGDGAASMN1; SMN2
SCHEMBL9788357 0.78 GPR139 (0.54) GPR139MEN1KMT2AATMHPGD
SCHEMBL8818729 0.74 HPGD (0.49) GPR139HPGDGAASMN1; SMN2
SCHEMBL8445815 0.72 GPR139 (0.55) GPR139MEN1KMT2AATMHPGD
SCHEMBL7897298 0.72 SMN1; SMN2 (0.69) GPR139MEN1KMT2AATMHPGD
SCHEMBL9788344 0.72 KDM4E (0.46) HPGDSMN1; SMN2
SCHEMBL23122290 0.70 GPR139 (0.54) GPR139MEN1KMT2AATMHPGD
SCHEMBL7932227 0.70 GPR139 (0.54) GPR139MEN1KMT2AATMHPGD
SCHEMBL23122289 0.70 GPR139 (0.54) GPR139MEN1KMT2AATMHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034408-A Fungicides of dihalocyclopropanoylamino acid amides BAYER AKTIENGESELLSCHAFT (DE) 1991-07-23 — — US claimed