Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 1/20 | 0.52 |
| ▸ | ACACA | Q13085 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CRHBP | P24387 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.51 |
| ▸ | PRCP | P42785 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7900323 | 0.86 | ACACA (0.56) | GPR139SMN1; SMN2HPGDGAAACACB | |
| SCHEMBL7897298 | 0.86 | SMN1; SMN2 (0.69) | GPR139SMN1; SMN2HPGDGAALMNA | |
| SCHEMBL7932227 | 0.84 | GPR139 (0.54) | GPR139SMN1; SMN2HPGDGAALMNA | |
| SCHEMBL23122289 | 0.84 | GPR139 (0.54) | GPR139SMN1; SMN2HPGDGAALMNA | |
| SCHEMBL23122290 | 0.84 | GPR139 (0.54) | GPR139SMN1; SMN2HPGDGAALMNA | |
| SCHEMBL7677571 | 0.83 | MEN1 (0.59) | GPR139SMN1; SMN2HPGDGAAACACB | |
| SCHEMBL7681216 | 0.83 | MEN1 (0.59) | GPR139SMN1; SMN2HPGDGAAACACB | |
| SCHEMBL8949273 | 0.83 | SMN1; SMN2 (0.53) | GPR139SMN1; SMN2HPGDGAALMNA | |
| SCHEMBL19658757 | 0.82 | HTT (0.71) | ACACBACACALMNAHTTALDH1A1 | |
| SCHEMBL14535437 | 0.82 | HTT (0.71) | ACACBACACALMNAHTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618907-B1 | 1-(ARYLALKYL-AMINOALKYL)IMIDAZOLE DERIVATIVES, PROCESSES OF PREPARATION AND USE AS THERAPEUTICAL AGENTS | BRITISH TECH GROUP INT (GB) | 1999-04-28 | — | — | EP | disclosed |