Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | F2 | P00734 | 4/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | HGFAC | Q04756 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4132832 | 0.94 | KMT2A (0.57) | KDM4EF2PRSS1KMT2APRSS2 | |
| SCHEMBL9788371 | 0.93 | F2 (0.58) | F2PRSS1KMT2APRSS2PRSS3 | |
| SCHEMBL6052916 | 0.92 | KMT2A (0.58) | KDM4EF2PRSS1KMT2APRSS2 | |
| SCHEMBL11649516 | 0.87 | KMT2A (0.60) | F2PRSS1KMT2APRSS2PRSS3 | |
| SCHEMBL27769736 | 0.87 | PARP10 (0.51) | KDM4EF2PRSS1KMT2APRSS2 | |
| SCHEMBL9003587 | 0.86 | PRSS1 (0.63) | F2PRSS1KMT2APRSS2PRSS3 | |
| SCHEMBL8585571 | 0.86 | PRSS1 (0.63) | F2PRSS1KMT2APRSS2PRSS3 | |
| SCHEMBL5698842 | 0.86 | KDM4E (0.65) | KDM4EF2PRSS1KMT2AMAPT | |
| SCHEMBL28624473 | 0.86 | KDM4E (0.57) | KDM4EKMT2AMAPTMEN1PARP10 | |
| SCHEMBL29637878 | 0.84 | MAPT (0.57) | KDM4EPRSS1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3279350-A | — | — | None | — | — | JP | disclosed |
| JP-H03279350-A | DIAMINE DERIVATIVE HAVING NAPHTHALENE SKELETON | NIPPON STEEL CHEM CO LTD | 1991-12-10 | — | — | JP | disclosed |