SCHEMBL4132832

SCHEMBL4132832

Nc1ccc(OC(=O)c2ccc(C(=O)Oc3ccc4cc(C(=O)O)ccc4c3)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.57
MAPT P10636 2/20 0.57
MEN1 O00255 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
KDM4E B2RXH2 1/20 0.54
F2 P00734 4/20 0.54
PRSS1 P07477 4/20 0.54
PRSS2 P07478 3/20 0.54
PRSS3 P35030 3/20 0.54
PKM P14618 1/20 0.54
NR1H4 Q96RI1 1/20 0.52
HGFAC Q04756 3/20 0.50
TMPRSS2 O15393 1/20 0.50
MLNR O43193 1/20 0.50
ALDH1A1 P00352 1/20 0.50
C1R P00736 1/20 0.50
F10 P00742 1/20 0.50
PLG P00747 1/20 0.50
F12 P00748 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6052916 0.98 KMT2A (0.58) KMT2AMAPTMEN1TDP1KDM4E
SCHEMBL9788373 0.94 KDM4E (0.53) KMT2AMAPTMEN1TDP1KDM4E
SCHEMBL6052888 0.90 KMT2A (0.68) KMT2AMAPTMEN1TDP1KDM4E
SCHEMBL5698841 0.89 KMT2A (0.66) KMT2AMAPTMEN1TDP1KDM4E
SCHEMBL13292773 0.87 KMT2A (0.64) KMT2AMAPTMEN1TDP1F2
SCHEMBL9788371 0.87 F2 (0.58) KMT2AMAPTMEN1TDP1F2
SCHEMBL5698842 0.87 KDM4E (0.65) KMT2AMAPTMEN1TDP1KDM4E
SCHEMBL9003587 0.87 PRSS1 (0.63) KMT2AMAPTMEN1TDP1F2
SCHEMBL8585571 0.87 PRSS1 (0.63) KMT2AMAPTMEN1TDP1F2
SCHEMBL10778099 0.85 KMT2A (0.77) KMT2AMAPTMEN1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1983020-B1 METHOD FOR MODIFICATION OF LIQUID CRYSTAL POLYMER LEF TECHNOLOGY INC (JP) 2014-05-07 EP disclosed
US-7608371-B2 Irradiating polyesters with laser beam having pulse width of 10-12 seconds or less to improve physical strength; abrasion resistance LEF TECHNOLOGY, INC. (JP) 2009-10-27 US disclosed
US-20090048362-A1 Method of Modifying Liquid Crystal Polymers LEF TECHNOLOGY, INC. (JP) 2009-02-19 US disclosed
EP-1983020-A1 METHOD FOR MODIFICATION OF LIQUID CRYSTAL POLYMER LEF Technology Inc. (JP) 2008-10-22 EP disclosed