SCHEMBL8585571

SCHEMBL8585571

Nc1ccc(C(=O)Oc2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRSS1 P07477 4/20 0.63
F2 P00734 3/20 0.63
PRSS2 P07478 3/20 0.63
PRSS3 P35030 3/20 0.63
KMT2A Q03164 3/20 0.63
PKM P14618 2/20 0.63
PARP10 Q53GL7 3/20 0.58
NR1H4 Q96RI1 1/20 0.53
HSD17B10 Q99714 2/20 0.50
PARP15 Q460N3 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
HGFAC Q04756 1/20 0.47
MEN1 O00255 1/20 0.47
ACR P10323 1/20 0.47
TMPRSS15 P98073 1/20 0.47
LMNA P02545 2/20 0.47
CYP1A2 P05177 2/20 0.47
CYP3A4 P08684 2/20 0.47
MAOA P21397 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9003587 1.00 PRSS1 (0.63) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL28858885 0.95 HSD17B10 (0.59) PRSS1F2PRSS2PRSS3KMT2A
Propane SCHEMBL8500769 0.93 PRSS1 (0.56) PRSS1F2PRSS2PRSS3KMT2A
Aminobenzoic Acid SCHEMBL31416072 0.93 PARP10 (0.59) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL347429 0.92 PRSS1 (0.71) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL346698 0.92 PRSS1 (0.71) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL107649 0.92 PRSS1 (0.71) PRSS1F2PRSS2PRSS3KMT2A
Butane SCHEMBL8503863 0.92 LMNA (0.55) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL376498 0.90 PARP10 (0.62) PRSS1F2PRSS2PRSS3KMT2A
SCHEMBL7536846 0.90 PARP10 (0.62) PRSS1F2PRSS2PRSS3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5928733-A Active-matrix liquid crystal display HITACHI, LTD. (JP) 1999-07-27 US disclosed
US-4277487-A SLOWING HEART RATE BOEHRINGER INGELHEIM GMBH (DE) 1981-07-07 US disclosed